
We all know that light effects the growth and development of plants, but what effect does light have on humans and animals? A new paper by Nathalie Hoang et al., published in PLoS Biology, explores this question by examining cryptochromes in flies, mice, and humans.
In plants, cryptochromes are photoreceptor proteins which absorb and process blue light for functions such as growth, seedling development, and leaf and stem expansion. Cryptochromes are present in humans and animals as well and have been proven to regulate the mechanisms of the circadian clock. But how they work in humans and animals is still somewhat of a mystery.
When plants are exposed to blue light, they experience a reduction in flavin pigments. This reduction activates the cryptochromes and thus allows for growth and seedling development. Hoang et al. sought to study the effect of blue light on fly, animal, and human cryptochromes by exposing them to blue light and measuring the change in the number of oxidized flavins. After a prolonged exposure to blue light, the authors found that the number of flavins did in fact decrease, as they do in plants.
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