World’s first schizophrenic mouse developed by gene modification | Kitty Mowmow's Animal Expo

World’s first schizophrenic mouse developed by gene modification

From the dawn of medical history, mice have always been a tool, used for the development of medical treatments and understanding of human anatomy. In medical history, mice models have greatly helped medical scientists to study mainly, structure and diseases related to heart, kidney and genes.

Scientists at John Hopkins University in Baltimore have another success in medical history as they bred world’s first schizophrenic or mentally ill mouse.

For the first time we have an animal genetically engineered with a mental illness. It will allow researchers to study the disease and develop treatments.

To develop this mouse, scientists modified its DNA to mimic the gene responsible for schizophrenia. This gene was inserted into the egg cell and then fertilized by using surrogate mothers. Features, such as hyperactivity and depression, similar to those humans with schizophrenia, were detected in mice’s brain.

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