Emotional ‘Bummer’ Of Cocaine Addiction Mimicked In Rats

Cocaine addicts often suffer a downward emotional spiral that is a key to their craving and chronic relapse. While researchers have developed animal models of the reward of cocaine, they have not been able to model this emotional impact, until now.

Regina Carelli and colleagues report experiments with rats in which they have mimicked the negative affect of cocaine addiction and even how it drives greater cocaine use. They said their animal model could enable better understanding of the emotional motivations of cocaine addiction and how to ameliorate them.

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